Flight Time from Buffalo to San Diego

At the moment, several airlines serve connecting flights from Buffalo to San Diego, including: American Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.

By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Buffalo to San Diego is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

The cheapest months to fly from Buffalo to San Diego is September, when demand for travel is lower.

After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Buffalo to San Diego on December 24, 2025 with United Airlines, with prices starting at SEK 2,165.

You can land at any one of the following hubs in San Diego, with Buffalo Niagara International Airport to San Diego International Airport (BUF-SAN) is by far the most common option on this route: San Diego International Airport (SAN) McClellan-Palomar Airport (CLD) Marine Corps Air Station Miramar (NKX).

The time difference between San Diego and Buffalo is 3h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.