Flights from Santa Maria(SMX) to John Wayne Airport(SNA)

By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santa Maria to Santa Ana is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

The cheapest months to fly from Santa Maria to Santa Ana is October, when demand for travel is lower.

After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Santa Maria to Santa Ana on April 9, 2026 with American Airlines, with prices starting at US$675.

The time difference between Santa Ana and Santa Maria is 0h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.