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O'Hare International Airport to Santa Ana flight
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Cheap Flights from O'Hare International Airport to Santa Ana

Search for flights from O'Hare International Airport to Santa Ana. Find affordable one-way or round-trip flights.

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • ORD09:36
        13h 54m
        1 stop
        SNA21:30
        Chicago - Santa Ana|Wed, May 29|Spirit Airlines
        US$52US$124
        57% OFF
        57% OFF
        US$124US$52
      • ORD22:52
        12h 37m
        1 stop
        SNA09:29
        Chicago - Santa Ana|Tue, Jun 4|Spirit Airlines
        US$58US$124
        54% OFF
        54% OFF
        US$124US$58
      • ORD18:27
        27h 14m
        1 stop
        SNA19:41
        Chicago - Santa Ana|Tue, May 7|Frontier Airlines
        US$67US$124
        46% OFF
        46% OFF
        US$124US$67
      • ORD22:52
        13h 11m
        1 stop
        SNA10:03
        Chicago - Santa Ana|Tue, May 21|Spirit Airlines
        US$70
        US$70
      • ORD22:52
        13h 11m
        1 stop
        SNA10:03
        Chicago - Santa Ana|Tue, May 14|Spirit Airlines
        US$72
        US$72
      • ORD08:00
        12h 22m
        1 stop
        SNA18:22
        Chicago - Santa Ana|Tue, Jun 18|Frontier Airlines
        US$79
        US$79
      • ORD13:13
        10h 17m
        1 stop
        SNA21:30
        Chicago - Santa Ana|Sat, May 11|Spirit Airlines
        US$82
        US$82
      • ORD19:59
        25h 55m
        1 stop
        SNA19:54
        Chicago - Santa Ana|Sat, May 25|Frontier Airlines
        US$85
        US$85
      • ORD22:52
        13h 11m
        1 stop
        SNA10:03
        Chicago - Santa Ana|Tue, May 28|Spirit Airlines
        US$87
        US$87
      • ORD20:23
        25h 3m
        1 stop
        SNA19:26
        Chicago - Santa Ana|Wed, Jun 12|Frontier Airlines
        US$89
        US$89
      • ORD13:00
        3h 5m
        Direct
        SNA14:00
        Chicago - Santa Ana|Sat, May 11|Spirit Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from O'Hare International Airport to Santa Ana

View airlines operating flights from O'Hare International Airport to Santa Ana. Compare prices and find the airline that meets your travel needs to enjoy a comfortable journey.

Frontier Airlines
From US$67
Spirit Airlines
From US$70
Delta Air Lines
From US$125
United Airlines
From US$133
American Airlines
From US$133
Alaska Airlines
From US$135
Sun Country Airlines
From US$147
Southwest Airlines
From US$180
ANA airlines
Find more flights and airlines

There are 1 airport(s) in Santa Ana. Discover the top routes now!

Discover different airports in Santa Ana. Find the best flight and transfer option, and plan your trip accordingly.

  • 0.89 km from downtown Santa Ana
    John Wayne Airport
    Tickets From
    US$67
Flight Schedule from O'Hare International Airport to Santa Ana

Check on the flight schedule from O'Hare International Airport to Santa Ana. Find the flight that matches your travel plan.

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA361

    American Airlines

    05:10

    ORD

    3.6h

    06:45

    PHX

    SMTWTFS
    Search

  2. AA2214

    American Airlines

    07:45

    PHX

    1.3h

    09:03

    SNA

    SMTWTFS

  3. AS333

    Alaska Airlines

    06:00

    ORD

    4.5h

    08:31

    SEA

    SMTWTFS
    Search

  4. AS1190

    Alaska Airlines

    10:57

    SEA

    2.8h

    13:47

    SNA

    SMTWTFS

  5. AA2838

    American Airlines

    07:12

    ORD

    3.6h

    08:50

    PHX

    ------S
    Search

  6. AA470

    American Airlines

    10:20

    PHX

    1.4h

    11:46

    SNA

    SMTWTF-

  7. AA2285

    American Airlines

    08:16

    ORD

    4.4h

    Direct

    10:40

    SNA

    SMTWTFS
    Search

  8. AS325

    Alaska Airlines

    08:35

    ORD

    4.6h

    11:09

    PDX

    SMTWTFS
    Search

  9. AS1058

    Alaska Airlines

    11:10

    PDX

    2.5h

    13:40

    SNA

    SMTWTFS

  10. AA2250

    American Airlines

    09:58

    ORD

    3.9h

    11:51

    PHX

    SMTWTFS
    Search

  11. F91719

    Frontier Airlines

    06:40

    PHX

    1.4h

    08:02

    SNA

    SMTWTF-

  12. AA2212

    American Airlines

    10:33

    ORD

    4.6h

    Direct

    13:07

    SNA

    SMTWTFS
    Search

  13. DL2087

    Delta Air Lines

    13:45

    ORD

    3.6h

    16:21

    SLC

    -MTWT--
    Search

  14. DL2077

    Delta Air Lines

    17:22

    SLC

    2.0h

    18:20

    SNA

    SMTWT-S

  15. AA1179

    American Airlines

    17:30

    ORD

    4.3h

    Direct

    19:45

    SNA

    SMTWTFS
    Search

  16. NK2525

    Spirit Airlines

    22:52

    ORD

    3.9h

    00:46

    LAS

    SMTWTFS
    Search

  17. NK876

    Spirit Airlines

    20:40

    LAS

    1.3h

    21:55

    SNA

    SMTWTFS
Find more flights and airlines

Flight Info of Flights from O'Hare International Airport to Santa Ana

Cheapest round-trip ticket price

$217

Cheapest nonstop flight price

$52

Off-season for travel

January

Peak season for travel

July

FAQs for O'Hare International Airport to Santa Ana Flights

  • What is the transportation method from the main airport to downtown in Santa Ana?

    • The distance from John Wayne Airport to downtown is about 7km. It takes about 20 minutes by taxi.

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