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Myrtle Beach International Airport to Des Moines International Airport flight
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Cheap Flights from Myrtle Beach International Airport to Des Moines International Airport

Search for flights from Myrtle Beach to Des Moines. Find affordable one-way or round-trip flights.

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • MYR17:45
        6h 29m
        1 stop
        DSM23:14
        Myrtle Beach - Des Moines|Sat, Jun 29|American Airlines
        €222€431
        49% OFF
        49% OFF
        €431€222
      • MYR13:05
        7h 23m
        1 stop
        DSM19:28
        Myrtle Beach - Des Moines|Wed, Jun 26|Delta Air Lines
        €233€431
        46% OFF
        46% OFF
        €431€233
      • MYR08:30
        8h
        1 stop
        DSM15:30
        Myrtle Beach - Des Moines|Sat, Jun 29|Delta Air Lines
        €259€431
        40% OFF
        40% OFF
        €431€259
      • MYR15:20
        7h 26m
        1 stop
        DSM21:46
        Myrtle Beach - Des Moines|Sat, Jun 29|United Airlines
        €259
        €259
      • MYR13:30
        5h 19m
        1 stop
        DSM17:49
        Myrtle Beach - Des Moines|Wed, Jun 26|United Airlines
        €262
        €262
      • MYR11:22
        4h 55m
        1 stop
        DSM15:17
        Myrtle Beach - Des Moines|Wed, Jun 26|American Airlines
        €273
        €273
      • MYR13:30
        9h 14m
        1 stop
        DSM21:44
        Myrtle Beach - Des Moines|Tue, Jun 25|United Airlines
        €295
        €295
      • MYR11:00
        5h 17m
        1 stop
        DSM15:17
        Myrtle Beach - Des Moines|Fri, Jul 19|American Airlines
        €300
        €300
      • MYR13:20
        9h 24m
        1 stop
        DSM21:44
        Myrtle Beach - Des Moines|Mon, Jul 1|United Airlines
        €305
        €305
      • MYR13:30
        9h 14m
        1 stop
        DSM21:44
        Myrtle Beach - Des Moines|Mon, Jun 24|United Airlines
        €315
        €315
      • MYR13:00
        3h 5m
        Direct
        DSM14:00
        Myrtle Beach - Des Moines|Mon, Jun 24|American Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Myrtle Beach International Airport to Des Moines International Airport

View airlines operating flights from Myrtle Beach to Des Moines. Compare prices and find the airline that meets your travel needs to enjoy a comfortable journey.

American Airlines
From €222
Delta Air Lines
From €233
Frontier Airlines
From €247
United Airlines
From €259
Sun Country Airlines
From €313
Southwest Airlines
From €379
Allegiant Air
From €588
ANA airlines

Find more flights and airlines

Flight Schedule from Myrtle Beach International Airport to Des Moines International Airport

Check on the flight schedule from Myrtle Beach to Des Moines to find the flight that matches your travel plan.

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3162

    Delta Air Lines

    06:00

    MYR

    1.3h

    07:19

    ATL

    SMTWTFS
    Search

  2. DL1704

    Delta Air Lines

    09:13

    ATL

    2.1h

    10:22

    DSM

    SMTWTFS

  3. AA2529

    American Airlines

    11:22

    MYR

    1.1h

    12:30

    CLT

    SMTWT-S
    Search

  4. AA2962

    American Airlines

    13:32

    CLT

    2.4h

    14:58

    DSM

    SMTWTFS

  5. AA5347

    American Airlines

    11:29

    MYR

    1.2h

    12:43

    CLT

    -----F-
    Search

  6. AA2962

    American Airlines

    13:32

    CLT

    2.4h

    14:58

    DSM

    SMTWTFS

  7. UA2278

    United Airlines

    13:30

    MYR

    2.4h

    14:54

    ORD

    SMTWTFS
    Search

  8. UA5283

    United Airlines

    16:20

    ORD

    1.5h

    17:49

    DSM

    SMTWT--

  9. DL3182

    Delta Air Lines

    14:49

    MYR

    1.3h

    16:09

    ATL

    SMTWTFS
    Search

  10. DL2086

    Delta Air Lines

    16:21

    ATL

    2.2h

    17:31

    DSM

    SMTWTFS

  11. DL1523

    Delta Air Lines

    17:19

    MYR

    3.1h

    19:23

    MSP

    SMTWTFS
    Search

  12. DL5253

    Delta Air Lines

    19:46

    MSP

    1.3h

    21:02

    DSM

    SMTWTFS

  13. AA2180

    American Airlines

    17:52

    MYR

    3.0h

    19:54

    DFW

    SMTWTFS
    Search

  14. AA1371

    American Airlines

    21:19

    DFW

    1.9h

    23:14

    DSM

    SMTWTFS

  15. AA5465

    American Airlines

    18:12

    MYR

    1.2h

    19:24

    CLT

    SMTWTFS
    Search

  16. AA1325

    American Airlines

    20:45

    CLT

    2.5h

    22:13

    DSM

    SMTWTFS

  17. DL3170

    Delta Air Lines

    18:57

    MYR

    1.4h

    20:20

    ATL

    SMTWTFS
    Search

  18. DL2306

    Delta Air Lines

    21:10

    ATL

    2.2h

    22:23

    DSM

    SMTWTFS

  19. AA1861

    American Airlines

    20:42

    MYR

    1.1h

    21:50

    CLT

    SMTWTFS
    Search

  20. AA1325

    American Airlines

    20:45

    CLT

    2.5h

    22:13

    DSM

    SMTWTFS
Find more flights and airlines

Myrtle Beach International Airport to Des Moines International Airport Flights Info

Flight distance1,561.76km
Cheapest one-way ticket price€221

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