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          Stays
          3~5 night
          Purpose of long stay
          e.g. Business Travel
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          Book Extended Stay Hotels in Cape Girardeau

          Recommended
          Price
          Star Rating
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          Pear Tree Inn Cape Girardeau Medical Center

          Cape Girardeau|5.08km from city center
          With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.Take advantage of recreation opportunities such as a seasonal outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area.Featured amenities include express check-out, a 24-hour front desk, and an elevator.Stay in one of 78 guestrooms featuring LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
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          Excellent

          100 Reviews

          4.3/5
          From$68
          Latest Price

          Drury Inn & Suites Cape Girardeau

          Cape Girardeau|5.57km from city center
          With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.Be sure to enjoy recreational amenities, including an indoor pool, a spa tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access and a television in a common area.Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.Featured amenities include a business center, express check-out, and a 24-hour front desk. Free self parking is available onsite.Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
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          Excellent

          100 Reviews

          4.5/5
          From$108
          Latest Price

          Courtyard Cape Girardeau Downtown

          Cape Girardeau|0.38km from city center
          Located in Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown is within a 15-minute walk of Shawnee National Forest and eDen Spa & Salon. This hotel is 0.7 mi (1.1 km) from Isle Casino Cape Girardeau and 0.7 mi (1.2 km) from Southeast Missouri State University.Enjoy recreation amenities such as a 24-hour fitness center or take in the view from a terrace. This hotel also features complimentary wireless internet access and gift shops/newsstands.Satisfy your appetite with American cuisine at The Bistro, a bistro which features a bar/lounge. Dining is also available at the coffee shop/cafe. Cooked-to-order breakfasts are served on weekdays from 6:30 AM to 9:30 AM and on weekends from 7:00 AM to 10:00 AM for a fee.Featured amenities include a 24-hour business center, dry cleaning/laundry services, and a 24-hour front desk. Free self parking is available onsite.Make yourself at home in one of the 91 guestrooms featuring refrigerators. Your bed comes with down comforters and Egyptian cotton sheets. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers.
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          Outstanding

          90 Reviews

          4.6/5
          From$149
          Latest Price

          Auburn Place Hotel & Suites Cape Girardeau

          Cape Girardeau|5.29km from city center
          With a stay at Auburn Place Hotel And Suites in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.9 mi (1.5 km) from Saint Francis Medical Center and 2.4 mi (3.8 km) from Saint Francis Healthcare System.Enjoy recreational amenities such as an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, barbecue grills, and a vending machine.Grab a bite from the grocery/convenience store serving guests of Auburn Place Hotel And Suites. A complimentary buffet breakfast is served daily.Featured amenities include complimentary wired internet access, a 24-hour business center, and dry cleaning/laundry services.Make yourself at home in one of the 133 air-conditioned rooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, and housekeeping is provided daily.
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          Very Good

          100 Reviews

          4.2/5
          From$89
          Latest Price

          Quality Inn

          Cape Girardeau|6.51km from city center
          With a stay at Quality Inn in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.6 mi (1 km) from Saint Francis Healthcare System and 0.8 mi (1.4 km) from Cape Splash Family Aquatic Center.Take advantage of recreation opportunities such as an outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area.A complimentary English breakfast is served daily from 6:00 AM to 10:00 AM.Featured amenities include complimentary wired internet access, a computer station, and a 24-hour front desk. Free self parking is available onsite.Make yourself at home in one of the 49 air-conditioned guestrooms. Your memory foam bed comes with down comforters and Egyptian cotton sheets. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair dryers.
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          71 Reviews

          3.5/5
          From$67
          Latest Price

          Pear Tree Inn Cape Girardeau West

          Cape Girardeau|5.54km from city center
          Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, within a 5-minute drive of Saint Francis Medical Center and Saint Francis Healthcare System. This hotel is 4.6 mi (7.5 km) from Shawnee National Forest and 5 mi (8.1 km) from Mississippi River.Take advantage of recreation opportunities such as a fitness center, or other amenities including complimentary wireless internet access and a television in a common area.A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM.Featured amenities include a 24-hour business center, a 24-hour front desk, and a safe deposit box at the front desk. Free self parking is available onsite.Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
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          Excellent

          100 Reviews

          4.3/5
          From$72
          Latest Price

          Drury Plaza Hotel Cape Girardeau Conference Center

          Cape Girardeau|5.44km from city center
          When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.Be sure to enjoy recreational amenities, including an indoor pool, a spa tub, and a fitness center.Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served daily.Featured amenities include a 24-hour business center, a 24-hour front desk, and laundry facilities. Event facilities at this hotel consist of a conference center and meeting rooms. Free self parking is available onsite.Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
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          Outstanding

          100 Reviews

          4.7/5
          From$122
          Latest Price

          Hampton Inn Cape Girardeau I-55 East

          Cape Girardeau|5.16km from city center
          With a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and a vending machine.Grab a bite from the snack bar/deli serving guests of Hampton Inn Cape Girardeau I 55 East. A complimentary continental breakfast is served daily from 6 AM to 10 AM.Featured amenities include complimentary wired internet access, a business center, and complimentary newspapers in the lobby. Free self parking is available onsite.Make yourself at home in one of the 86 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
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          Outstanding

          100 Reviews

          4.7/5
          SOLD OUT

          Holiday Inn Express & Suites Cape Girardeau I-55

          Cape Girardeau|5.2km from city center
          When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee National Forest and Mississippi River. This spa hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.Take time to pamper yourself with a visit to the full-service spa. If you're looking for recreational opportunities, you'll find an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access and a vending machine.A complimentary breakfast is included.Featured amenities include complimentary wired internet access, a business center, and complimentary newspapers in the lobby. Planning an event in Cape Girardeau? This hotel has 118 square feet (11 square meters) of space consisting of conference space and a meeting room. Free self parking is available onsite.Make yourself at home in one of the 102 guestrooms featuring microwaves and flat-screen televisions. Your pillowtop bed comes with down comforters and premium bedding. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers.
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          Outstanding

          100 Reviews

          4.6/5
          From$129
          Latest Price

          Candlewood Suites Cape Girardeau

          Cape Girardeau|5.14km from city center
          With a stay at Candlewood Suites Cape Girardeau, an IHG Hotel in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 3 mi (4.9 km) from Saint Francis Healthcare System.Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and barbecue grills.Grab a bite from the grocery/convenience store serving guests of Candlewood Suites Cape Girardeau, an IHG Hotel.Featured amenities include a business center, complimentary newspapers in the lobby, and dry cleaning/laundry services. Free self parking is available onsite.Make yourself at home in one of the 85 air-conditioned rooms featuring kitchens with full-sized refrigerators/freezers and stovetops. 32-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include safes and desks, and housekeeping is provided weekly.
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          Very Good

          95 Reviews

          4.0/5
          From$88
          Latest Price

          See all hotels in Cape Girardeau

          Extended Stay Hotels in Cape Girardeau&Guest User Reviews

          Courtyard Cape Girardeau Downtown
          4.6/590 Reviews
          Cape Girardeau
          |0.38km from city center
          This is a great Marriott property just a few blocks from the core of the Cape. Spacious parking area, appealing lobby, friendly check in, lovely rooms, this has everything going for it. We like the repurposed buildings, in this case an old bank. Great value for breakfast sandwiches in the lobby, though they should offer complimentary coffee. Quiet, clean, historic, it has everything going for it in a super cute town. Would definitely stay here again.
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          From$149
          Candlewood Suites Cape Girardeau
          4/595 Reviews
          Cape Girardeau
          |5.14km from city center
          Room was spotlessly clean. Love these little kitchenette set ups as I pack as much healthy food as I can for my time on the road & the full size fridge is handy. Slept well on very comfortable bed w/triple sheets & lots of fat, fluffy pillows. Free wifi w/great signal, plenty of easily accessible outlets and enough work space to attend to business without feeling cramped. But more importantly, I cannot begin to say enough nice things about the young men at the front desk. Jason was the perfect combination of friendly & efficient at check-in, which is a welcome relief after a long day on the road. Next morning, John went out of his way on my behalf & printed off some much needed paperwork with cheery ”No problem, glad to help you out!” and I was quickly on my way. Highly recommend & will definitely be my first choice next time I'm in the area.
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          From$88
          Town House Inn Cape Girardeau
          2.6/520 Reviews
          Cape Girardeau
          |3.23km from city center
          this is a nice hotel. there is a restaurant next to it.
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          From$75
          Quality Inn
          3.5/571 Reviews
          Cape Girardeau
          |6.51km from city center
          The front desk staff was very friendly. There was a sign stating they did not offer housekeeping due to Covid-19 but our room was clean, despite that “ moldy old-hotel” smell which eventually disappeared. The only real issues was the beds—the mattress sits on top of some type of metal pedestal. When you rolled over it made a sound like metallic thunder or popping sheet metal. Both beds made the sound but one more so than the other. We also heard the same sound through the walls so I know it was not an isolated issue and there would be no reason to complain about it. The beds are comfy even if you feel like there is an thunderstorm happening outside. The room was booked for queen sized beds but I am pretty sure they were actually full size. (I sleep on a queen size and these beds seemed to be quite smaller.) That was not such a big deal but it could be an issue if there is two people sharing a bed. I appreciated the later breakfast hours of 7a-10a, instead of the customary 6-9.
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          From$67

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