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Knoxville to Des Moines International Airport flight
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Cheap Flights from Knoxville to Des Moines International Airport

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • TYS10:55
        4h 24m
        1 stop
        DSM14:19
        Knoxville - Des Moines|Thu, Jul 4|United Airlines
        €137€314
        56% OFF
        56% OFF
        €314€137
      • TYS12:14
        6h 25m
        1 stop
        DSM17:39
        Knoxville - Des Moines|Mon, Sep 2|Delta Air Lines
        €214€314
        32% OFF
        32% OFF
        €314€214
      • TYS07:00
        4h 33m
        1 stop
        DSM10:33
        Knoxville - Des Moines|Mon, Sep 2|United Airlines
        €226€314
        28% OFF
        28% OFF
        €314€226
      • TYS07:00
        4h 24m
        1 stop
        DSM10:24
        Knoxville - Des Moines|Wed, Jun 26|United Airlines
        €233
        €233
      • TYS07:00
        4h 24m
        1 stop
        DSM10:24
        Knoxville - Des Moines|Thu, Jun 27|United Airlines
        €233
        €233
      • TYS06:00
        18h 46m
        1 stop
        DSM23:46
        Knoxville - Des Moines|Thu, Jun 27|Allegiant Air
        €243
        €243
      • TYS10:41
        6h 14m
        1 stop
        DSM15:55
        Knoxville - Des Moines|Thu, Jul 4|American Airlines
        €253
        €253
      • TYS18:11
        6h 54m
        1 stop
        DSM00:05
        Knoxville - Des Moines|Sat, Jun 8|American Airlines
        €254
        €254
      • TYS18:11
        6h 54m
        1 stop
        DSM00:05
        Knoxville - Des Moines|Wed, Jun 26|American Airlines
        €254
        €254
      • TYS18:11
        6h 54m
        1 stop
        DSM00:05
        Knoxville - Des Moines|Thu, Jun 27|American Airlines
        €254
        €254
      • TYS13:00
        3h 5m
        Direct
        DSM14:00
        Knoxville - Des Moines|Fri, Jun 14|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Knoxville to Des Moines International Airport
United Airlines
From €137
Delta Air Lines
From €214
Allegiant Air
From €243
American Airlines
From €253
ANA airlines

Find more flights and airlines

There are 1 airport(s) in Knoxville. Discover the top routes now!

  • 0.73 km from downtown Knoxville
    Mcghee Tyson Airport
    Tickets From
    €137
Flight Schedule from Knoxville to Des Moines International Airport
Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3015

    Delta Air Lines

    05:25

    TYS

    1.0h

    06:25

    ATL

    SMTWTFS
    Search

  2. DL1704

    Delta Air Lines

    09:06

    ATL

    2.1h

    10:15

    DSM

    SMTWTFS

  3. DL5523

    Delta Air Lines

    06:33

    TYS

    2.5h

    08:01

    MSP

    SMTWTFS
    Search

  4. DL4998

    Delta Air Lines

    10:00

    MSP

    1.2h

    11:13

    DSM

    SMTWTFS

  5. DL5317

    Delta Air Lines

    07:00

    TYS

    1.1h

    08:05

    ATL

    SMTWTFS
    Search

  6. DL1704

    Delta Air Lines

    09:06

    ATL

    2.1h

    10:15

    DSM

    SMTWTFS

  7. UA5804

    United Airlines

    07:00

    TYS

    2.0h

    07:59

    ORD

    SMTWTFS
    Search

  8. UA2099

    United Airlines

    09:03

    ORD

    1.4h

    10:27

    DSM

    SMTWTF-

  9. DL4807

    Delta Air Lines

    07:45

    TYS

    1.8h

    09:30

    DTW

    SMTWTFS
    Search

  10. DL5058

    Delta Air Lines

    08:45

    DTW

    1.8h

    09:34

    DSM

    SMTWTFS

  11. AA5208

    American Airlines

    09:00

    TYS

    1.4h

    10:25

    CLT

    SMTWTFS
    Search

  12. AA2962

    American Airlines

    13:32

    CLT

    2.4h

    14:57

    DSM

    SMTWTFS

  13. AA5274

    American Airlines

    11:03

    TYS

    1.4h

    12:28

    CLT

    SMTWTFS
    Search

  14. AA2962

    American Airlines

    13:32

    CLT

    2.4h

    14:57

    DSM

    SMTWTFS

  15. AA5458

    American Airlines

    17:03

    TYS

    1.7h

    18:43

    DCA

    SMTW--S
    Search

  16. AA4408

    American Airlines

    19:50

    DCA

    2.7h

    21:31

    DSM

    SMTWTFS

  17. UA5305

    United Airlines

    17:55

    TYS

    2.0h

    18:55

    ORD

    SMTWTFS
    Search

  18. UA1576

    United Airlines

    20:20

    ORD

    1.4h

    21:44

    DSM

    SMTWTFS

  19. AA2257

    American Airlines

    19:49

    TYS

    1.2h

    20:59

    CLT

    SMTWTFS
    Search

  20. AA1325

    American Airlines

    20:45

    CLT

    2.5h

    22:15

    DSM

    SMTWTFS
Find more flights and airlines

Flight Info of Flights from Knoxville to Des Moines International Airport

Cheapest nonstop flight price

€136

Off-season for travel

January

Peak season for travel

April

FAQs for Knoxville to Des Moines International Airport Flights

  • When are flight tickets from Knoxville (TYS) to Des Moines (DSM) the cheapest?

    Airlines adjust prices for flights from Knoxville to Des Moines based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to Des Moines (DSM) cost?

    According to Trip.com's data, the lowest price is around €440.

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