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Des Moines to Buffalo Niagara International Airport flight
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Cheap Flights from Des Moines to Buffalo Niagara International Airport

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • DSM21:34
        19h 33m
        1 stop
        BUF18:07
        Des Moines - Buffalo|Fri, May 17|Frontier Airlines
        US$125US$333
        62% OFF
        62% OFF
        US$333US$125
      • DSM08:01
        6h 38m
        1 stop
        BUF15:39
        Des Moines - Buffalo|Tue, May 14|American Airlines
        US$133US$333
        60% OFF
        60% OFF
        US$333US$133
      • DSM18:50
        4h 6m
        1 stop
        BUF23:56
        Des Moines - Buffalo|Wed, Jul 3|United Airlines
        US$164US$333
        51% OFF
        51% OFF
        US$333US$164
      • DSM13:28
        18h 58m
        2 stops
        BUF09:26
        Des Moines - Buffalo|Wed, Jul 3|Frontier Airlines
        US$175
        US$175
      • DSM07:28
        5h 9m
        1 stop
        BUF13:37
        Des Moines - Buffalo|Thu, Jun 27|Delta Air Lines
        US$228
        US$228
      • DSM11:37
        4h 12m
        1 stop
        BUF16:49
        Des Moines - Buffalo|Fri, May 17|United Airlines
        US$238
        US$238
      • DSM08:00
        7h 49m
        1 stop
        BUF16:49
        Des Moines - Buffalo|Thu, May 16|United Airlines
        US$256
        US$256
      • DSM11:37
        4h 12m
        1 stop
        BUF16:49
        Des Moines - Buffalo|Tue, May 14|United Airlines
        US$256
        US$256
      • DSM18:13
        3h 34m
        1 stop
        BUF22:47
        Des Moines - Buffalo|Sun, Jun 23|American Airlines
        US$258
        US$258
      • DSM16:02
        7h 21m
        1 stop
        BUF00:23
        Des Moines - Buffalo|Thu, Jun 27|American Airlines
        US$276
        US$276
      • DSM13:00
        3h 5m
        Direct
        BUF14:00
        Des Moines - Buffalo|Sat, May 18|Frontier Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Des Moines to Buffalo Niagara International Airport
Frontier Airlines
From US$125
American Airlines
From US$133
United Airlines
From US$164
Delta Air Lines
From US$228
ANA airlines
Find more flights and airlines

There are 1 airport(s) in Des Moines. Discover the top routes now!

  • 0.83 km from downtown Des Moines
    Des Moines International Airport
    Tickets From
    US$125
Flight Schedule from Des Moines to Buffalo Niagara International Airport
Flight info.
Departure
Arrival
Weekly Schedule

  1. AA5414

    American Airlines

    06:02

    DSM

    2.4h

    09:28

    DCA

    SMTWTFS
    Search

  2. AA4436

    American Airlines

    09:59

    DCA

    1.4h

    11:26

    BUF

    SMTWTFS

  3. AA846

    American Airlines

    06:02

    DSM

    1.4h

    07:23

    ORD

    SMTWTFS
    Search

  4. AA3410

    American Airlines

    08:14

    ORD

    1.7h

    10:55

    BUF

    SMTWTFS

  5. DL5414

    Delta Air Lines

    06:30

    DSM

    1.8h

    09:19

    DTW

    SMTWTFS
    Search

  6. DL5474

    Delta Air Lines

    12:20

    DTW

    1.2h

    13:31

    BUF

    SMTWT-S

  7. DL5414

    Delta Air Lines

    06:30

    DSM

    1.8h

    09:19

    DTW

    SMTWTFS
    Search

  8. DL989

    Delta Air Lines

    10:30

    DTW

    1.1h

    11:34

    BUF

    -----F-

  9. DL4932

    Delta Air Lines

    07:27

    DSM

    2.8h

    11:14

    LGA

    SMTWT--
    Search

  10. AA4496

    American Airlines

    16:10

    LGA

    1.3h

    17:27

    BUF

    SMTWTFS

  11. DL4932

    Delta Air Lines

    07:27

    DSM

    2.8h

    11:14

    LGA

    SMTWT--
    Search

  12. DL5277

    Delta Air Lines

    12:59

    LGA

    1.5h

    14:28

    BUF

    SMTWT-S

  13. AA4795

    American Airlines

    07:39

    DSM

    2.7h

    11:19

    LGA

    SMTWT-S
    Search

  14. AA4496

    American Airlines

    16:10

    LGA

    1.3h

    17:27

    BUF

    SMTWTFS

  15. UA783

    United Airlines

    11:32

    DSM

    1.5h

    13:00

    ORD

    SMTWTFS
    Search

  16. UA561

    United Airlines

    14:15

    ORD

    1.6h

    16:54

    BUF

    SMTWTFS

  17. AA2962

    American Airlines

    15:07

    DSM

    2.4h

    18:30

    CLT

    SMTWTFS
    Search

  18. AA703

    American Airlines

    22:59

    CLT

    1.9h

    00:51

    BUF

    SMTWTFS

  19. DL4952

    Delta Air Lines

    17:09

    DSM

    1.8h

    19:58

    DTW

    SMTWT-S
    Search

  20. DL2717

    Delta Air Lines

    21:54

    DTW

    1.1h

    22:59

    BUF

    SMTWTFS
Find more flights and airlines

Flight Info of Flights from Des Moines to Buffalo Niagara International Airport

Cheapest nonstop flight price

$125

Off-season for travel

May

Peak season for travel

November

FAQs for Des Moines to Buffalo Niagara International Airport Flights

  • When are flight tickets from Des Moines (DSM) to Buffalo (BUF) the cheapest?

    Airlines adjust prices for flights from Des Moines to Buffalo based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to Buffalo (BUF) cost?

    According to Trip.com's data, the lowest price is around $459.

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