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Des Moines International Airport to Manchester-Boston Regional Airport flight
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Cheap Flights from Des Moines International Airport to Manchester-Boston Regional Airport

Search for flights from Des Moines to Manchester. Find affordable one-way or round-trip flights.

  • One way
  • Round-trip
sortSort by: Lowest Price
  • Sort by: Lowest Price
  • Sort by: Earliest Flight
      • DSM18:28
        5h 17m
        1 stop
        MHT00:45
        Des Moines - Manchester|Sat, Jun 22|American Airlines
        US$327US$502
        35% OFF
        35% OFF
        US$502US$327
      • DSM06:00
        7h 34m
        1 stop
        MHT14:34
        Des Moines - Manchester|Sun, Jul 7|American Airlines
        US$403US$502
        20% OFF
        20% OFF
        US$502US$403
      • DSM16:04
        7h 41m
        1 stop
        MHT00:45
        Des Moines - Manchester|Fri, Jun 28|American Airlines
        US$407US$502
        19% OFF
        19% OFF
        US$502US$407
      • DSM13:00
        3h 5m
        Direct
        MHT14:00
        Des Moines - Manchester|Fri, Jun 28|American Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Des Moines International Airport to Manchester-Boston Regional Airport

View airlines operating flights from Des Moines to Manchester. Compare prices and find the airline that meets your travel needs to enjoy a comfortable journey.

American Airlines
From US$327
Southwest Airlines
From US$418
United Airlines
From US$582
Frontier Airlines
From US$889
ANA airlines

Find more flights and airlines

Flight Schedule from Des Moines International Airport to Manchester-Boston Regional Airport

Check on the flight schedule from Des Moines to Manchester to find the flight that matches your travel plan.

Flight info.
Departure
Arrival
Weekly Schedule

  1. WN2762

    Southwest Airlines

    05:50

    DSM

    1.1h

    06:55

    STL

    SMTWTFS
    Search

  2. WN1335

    Southwest Airlines

    12:10

    STL

    1.1h

    13:15

    MDW

    -MT----

  3. WN1390

    Southwest Airlines

    20:20

    MDW

    2.1h

    23:25

    MHT

    SMTWTFS

  4. AA3418

    American Airlines

    05:54

    DSM

    1.4h

    07:21

    ORD

    SMTWTFS
    Search

  5. AA4149

    American Airlines

    17:45

    ORD

    2.3h

    21:00

    MHT

    SMTWTFS

  6. AA4406

    American Airlines

    06:03

    DSM

    2.4h

    09:29

    DCA

    SMTWTFS
    Search

  7. AA5404

    American Airlines

    13:01

    DCA

    1.7h

    14:43

    MHT

    SMTWT-S

  8. AA4406

    American Airlines

    06:03

    DSM

    2.4h

    09:29

    DCA

    SMTWTFS
    Search

  9. AA5150

    American Airlines

    10:02

    DCA

    1.7h

    11:43

    MHT

    SMTWTFS

  10. UA1568

    United Airlines

    15:19

    DSM

    1.5h

    16:50

    ORD

    ---W---
    Search

  11. UA1484

    United Airlines

    20:02

    ORD

    2.5h

    23:30

    EWR

    SMTWT-S

  12. UA4502

    United Airlines

    09:15

    EWR

    1.3h

    10:33

    MHT

    SMTWTFS

  13. AA2962

    American Airlines

    15:45

    DSM

    2.3h

    19:04

    CLT

    SMTWTFS
    Search

  14. AA5033

    American Airlines

    22:29

    CLT

    2.3h

    00:48

    MHT

    SMTWTFS

  15. AA4435

    American Airlines

    15:49

    DSM

    2.4h

    19:15

    DCA

    SMTWTFS
    Search

  16. AA5135

    American Airlines

    22:10

    DCA

    1.6h

    23:49

    MHT

    SMTWT-S

  17. WN776

    Southwest Airlines

    18:40

    DSM

    1.1h

    19:45

    STL

    SMTWT-S
    Search

  18. WN2530

    Southwest Airlines

    20:00

    STL

    2.4h

    23:25

    MCO

    SMTWTFS

  19. WN1757

    Southwest Airlines

    08:00

    MCO

    2.9h

    10:55

    MHT

    SMTWTFS

  20. UA5631

    United Airlines

    18:41

    DSM

    1.5h

    20:12

    ORD

    SMT-T--
    Search

  21. UA1774

    United Airlines

    21:35

    ORD

    2.3h

    00:55

    EWR

    SMTWTFS

  22. UA4502

    United Airlines

    09:15

    EWR

    1.3h

    10:33

    MHT

    SMTWTFS

  23. UA5307

    United Airlines

    18:50

    DSM

    1.6h

    20:23

    ORD

    ---W---
    Search

  24. UA1774

    United Airlines

    21:35

    ORD

    2.3h

    00:55

    EWR

    SMTWTFS

  25. UA4502

    United Airlines

    09:15

    EWR

    1.3h

    10:33

    MHT

    SMTWTFS
Find more flights and airlines

Des Moines International Airport to Manchester-Boston Regional Airport Flights Info

Flight distance1,831.89km
Cheapest one-way ticket price$326

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