Best Hotels in Cape Girardeau

From our daily free hot breakfast to our nightly cookie hour, Tru Cape Girardeau makes you feel at home. Located just off Interstate 55 at exit 99, we are conveniently located near the Cape Girardeau Sportsplex, Southeast Missouri State University, and the Conservation Nature Center. This beautiful hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. Stay connected to the office with free WiFi in every room or work from one of our quant business nooks located in the lobby. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns.

With a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.6 mi (1 km) from Saint Francis Healthcare System and 0.9 mi (1.4 km) from Cape Splash Family Aquatic Center. Take advantage of recreation opportunities such as an outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area. A complimentary English breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include complimentary wired internet access, a computer station, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 49 air-conditioned guestrooms. Your memory foam bed comes with down comforters and Egyptian cotton sheets. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair dryers.

Experience the character of a thoughtfully restored property at our hotel in downtown Cape Girardeau, where historic charm blends seamlessly with modern comfort. Our Cape Girardeau, MO hotel​ places you steps from local restaurants, unique bars, and cultural destinations, along with convenient access to the Southeast Missouri State University campus. You can start or end your day at The Bistro, offering balanced breakfast and dinner options alongside a full bar featuring a curated bourbon selection. After exploring the neighborhood, retreat to well‑designed guest rooms and suites with plush bedding and city views that create a relaxing space to unwind. A spacious 24‑hour fitness center helps you stay on track with your routine. Our family friendly hotel in downtown Cape Girardeau, will be loved by adults and children of all ages. The property also provides versatile event space ideal for small to mid‑sized meetings. Your stay at Courtyard Cape Girardeau Downtown is crafted for comfort and ease.

When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Shawnee National Forest and Mississippi River. This casino hotel is 0.1 mi (0.2 km) from Riverfront Park and 0.1 mi (0.2 km) from Isle Casino Cape Girardeau. Take advantage of recreation opportunities such as a casino, or other amenities including complimentary wireless internet access and gift shops/newsstands. Additional features at this hotel include wedding services, a television in a common area, and a vending machine. Enjoy American cuisine at Beacon 53, one of the hotel's many dining establishments, which include 2 restaurants and a coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. To-go breakfasts are available daily from 5:00 AM to 1:00 PM for a fee. Featured amenities include a 24-hour front desk, luggage storage, and ATM/banking services. Planning an event in Cape Girardeau? This hotel has 7450 square feet (692 square meters) of space consisting of a conference center and meeting rooms. Free self parking is available onsite. Make yourself at home in one of the 69 air-conditioned rooms featuring LED televisions. Your pillowtop bed comes with premium bedding. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have showers and hair dryers.

Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!

Welcome to your home away from home in Historic Cape Girardeau. Relax in our Indoor Heated Pool, challenge friends in the Arcade Game Room, or unwind on the Outdoor Gazebo Grill Patio. Take advantage of our Free Guest Laundry, Business Center, Meeting Room, and 24-hour Fitness Center. Stay connected with complimentary high-speed wireless Internet throughout your stay. While we do not serve breakfast, our convenient cupboard shop offers a variety of grab-and-go breakfast items for purchase to start your day your way. Experience the comfort of our full kitchen suites, perfect for extended stays or travelers seeking a home-like atmosphere. Our newly renovated hotel is ideally located just off I-55, providing easy access to St. Francis, Mercy, and Landmark Hospitals, the Regional Airport, and the vibrant Historic Downtown District. Cape Girardeau offers a rich blend of attractions for both business and leisure travelers. Catch thrilling sporting events and cultural performances year-round at nearby Southeast Missouri State University. Explore the scenic Mississippi Riverfront, enjoy a round of golf at local courses, or try your luck at Century Casino. Nature enthusiasts will appreciate the nearby Trail of Tears State Park and numerous city parks, including the Cape Girardeau SPORTSPLEX and Shawnee Park Sports Complex. Don’t miss seasonal events such as the Cape Girardeau Oktoberfest, River Heritage Festival, and the annual Christmas Traditions.

incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you’re pressed for time, grab Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed® watching the 37-inch HDTV or with your laptop on the provided lap desk.

With a stay at Rockwood Inn in Cape Girardeau, you'll be within a 5-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.2 mi (0.4 km) from Southeast Missouri State University and 0.7 mi (1.2 km) from Show Me Center. Take in the views from a garden and make use of amenities such as complimentary wireless internet access and a picnic area. Free self parking is available onsite. Make yourself at home in one of the 7 air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected.

When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System. Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall. Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include a 24-hour business center, a 24-hour front desk, and laundry facilities. Event facilities at this hotel consist of a conference center and meeting rooms. Free self parking is available onsite. Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.

Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System. This hotel is 4.5 mi (7.2 km) from Shawnee National Forest and 4.8 mi (7.8 km) from Mississippi River. Make use of convenient amenities, which include complimentary wireless internet access and a television in a common area. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM. Featured amenities include a 24-hour business center, a 24-hour front desk, and a safe deposit box at the front desk. Free self parking is available onsite. Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.