Hotels in Mytilene

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19 Best Hotels in Mytilene

Find great hotels in Mytilene on Trip.com! Check guest reviews, latest prices and hotel details to pick your perfect stay.
Top Picks
Lowest Price
Closest to Downtown
Top Reviewed
Heliotrope the Studios Hotels in Mytilene
Heliotrope the Studios Hotels in MytileneHeliotrope the Studios Hotels in MytileneHeliotrope the Studios Hotels in MytileneHeliotrope the Studios Hotels in MytileneHeliotrope the Studios Hotels in MytileneHeliotrope the Studios Hotels in Mytilene
49
Hotels in Mytilene
"The hotel is very comfortable and comfortable."
Very Good
14 reviews
8.9/10
1 night
From US$73
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Elysion Hotel Hotels in Mytilene
Elysion Hotel Hotels in MytileneElysion Hotel Hotels in MytileneElysion Hotel Hotels in MytileneElysion Hotel Hotels in MytileneElysion Hotel Hotels in MytileneElysion Hotel Hotels in Mytilene
99+
Hotels in Mytilene
Trip.BestNo. 2 of 4-Star Select Hotels in North Aegean
Located in Lesvos, Elysion Hotel is within a 10-minute drive of Teriade Museum and Bus Station. This beach hotel is 2.9 mi (4.7 km) from University of the Aegean and 4.2 mi (6.8 km) from Port of Mytilene. Enjoy recreational amenities such as outdoor tennis courts and an outdoor pool. Additional features at this hotel include complimentary wireless internet access, concierge services, and wedding services. Getting to nearby attractions is a breeze with the area shuttle (surcharge). Grab a bite to eat at one of the hotel's 2 restaurants, or stay in and take advantage of the 24-hour room service. Snacks are also available at the coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. A complimentary buffet breakfast is included. Featured amenities include complimentary wired internet access, a 24-hour business center, and complimentary newspapers in the lobby. Planning an event in Lesvos? This hotel has 151 square feet (14 square meters) of space consisting of conference space and a meeting room. A roundtrip airport shuttle is provided for a surcharge (available 24 hours), and free valet parking is available onsite. Make yourself at home in one of the 35 guestrooms featuring refrigerators and minibars. Your Select Comfort bed comes with premium bedding. Rooms have private furnished balconies. Wired and wireless internet access is complimentary, while 32-inch LCD televisions with satellite programming provide entertainment. Private bathrooms have complimentary toiletries and hair dryers.
Great
18 reviews
9.0/10
1 night
From US$103
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Studio Ermou Mytilene Center Hotels in Mytilene
Studio Ermou Mytilene Center Hotels in MytileneStudio Ermou Mytilene Center Hotels in MytileneStudio Ermou Mytilene Center Hotels in Mytilene
4
Very Good
8.5/10
1 night
From US$47
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Blue Sea Hotel Hotels in Mytilene
Blue Sea Hotel Hotels in MytileneBlue Sea Hotel Hotels in MytileneBlue Sea Hotel Hotels in MytileneBlue Sea Hotel Hotels in MytileneBlue Sea Hotel Hotels in MytileneBlue Sea Hotel Hotels in Mytilene
38
Hotels in Mytilene
"Midilli şehrinde iyi konumda memnun kaldığımız bir otel bir daha Midilli ye gidersem adresim mutlaka bu otel olacak.Rezervasyonumuzda çok yardımcı olan Trip com 'a da çok teşekkür ederiz"
Very Good
16 reviews
8.3/10
1 night
From US$60
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The Loriet Hotels in Mytilene
The Loriet Hotels in MytileneThe Loriet Hotels in MytileneThe Loriet Hotels in MytileneThe Loriet Hotels in MytileneThe Loriet Hotels in MytileneThe Loriet Hotels in Mytilene
99+
Hotels in Mytilene
"I'm sure they are amazing for summer time. But for winter time they have some disadvantages. If you need a hotel just for sleep. Thats good. +Excellent breakfast x2 +Comfortable bed +Air conditioner enough for bed side. +Good price +Amazing garden +Friendly workers +Amazing breakfast place -I selected that room because the photos show that room with a chimney. But in reality there is no chimney -city center 40 min walking / 6x2 euro taxi price -Air-conditioning is not enough for the entire room and banio but it's enough for sleeping. We couldn't take a shower or sit in the room because it was cold. -Water heating systems have a problem that water is getting cold usually -amazing garden means bugs.. we killed a cockroach inside the banio in morning but maybe we were unlucky because the room looks clean. I'm not sure. -wifi problems but maybe we were unlucky : summary; I prefer that room in winter time for 1 night. Good price and breakfast. But if you want to spend time inside the hotel. They need a better Air-conditioning system"
Very Good
53 reviews
8.5/10
1 night
From US$80
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Mythical Coast Wellness Retreat Hotels in Mytilene
Mythical Coast Wellness Retreat Hotels in MytileneMythical Coast Wellness Retreat Hotels in MytileneMythical Coast Wellness Retreat Hotels in MytileneMythical Coast Wellness Retreat Hotels in MytileneMythical Coast Wellness Retreat Hotels in MytileneMythical Coast Wellness Retreat Hotels in Mytilene
99+
Hotels in Mytilene
Trip.BestNo. 4 of Premium Hotels in North Aegean
"Πολύ όμορφο δωμάτιο και ευρύχωρος ο χώρος του πρωινού και το lounge. Η πισίνα αρκετά μεγάλη. Η junior σουίτα θα μπορούσε να ειναι και λίγο μεγαλύτερη ώστε να είναι πιο άνετη για 3μελή οικογένεια. Το πρωινό καταπληκτικό. Οι εγκαταστάσεις και οι παροχές spa εξαιρετικές."
Very Good
66 reviews
8.0/10
1 night
From US$104
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Agora Apartments Hotels in Mytilene
Agora Apartments Hotels in MytileneAgora Apartments Hotels in MytileneAgora Apartments Hotels in MytileneAgora Apartments Hotels in MytileneAgora Apartments Hotels in MytileneAgora Apartments Hotels in Mytilene
99+
Hotels in Mytilene
With a stay at Agora Apartments in Lesvos, you'll be within a 5-minute walk of Theophilos Museum and Theriade Library and Museum of Modern Art. This guesthouse is 28.2 mi (45.3 km) from Badavut Beach and 29.2 mi (46.9 km) from Sarimsakli Beach. Take in the views from a terrace and make use of amenities such as complimentary wireless internet access. Make yourself at home in one of the 4 air-conditioned rooms featuring kitchens with full-sized refrigerators/freezers and ovens. Complimentary wireless internet access is available to keep you connected. Conveniences include safes and microwaves, and housekeeping is provided on request.
Amazing
1 review
9.7/10
1 night
From US$111
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Eleofilos Old Town Hotels in Mytilene
Hotels in Mytilene
Eleofilos Old Town is the perfect place to unwind after a day of travel or work.
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Theofilos Paradise Boutique Hotel Hotels in Mytilene
Theofilos Paradise Boutique Hotel Hotels in MytileneTheofilos Paradise Boutique Hotel Hotels in MytileneTheofilos Paradise Boutique Hotel Hotels in MytileneTheofilos Paradise Boutique Hotel Hotels in MytileneTheofilos Paradise Boutique Hotel Hotels in MytileneTheofilos Paradise Boutique Hotel Hotels in Mytilene
99+
Hotels in Mytilene
Trip.BestNo. 3 of 4-Star Select Hotels in North Aegean
"At the bottom of the hotel market. At the distance of walking to the port. The rooms are clean. Breakfast is open to the buffet and a variety of food. The pool is small. If two people enter, it is filled. All rooms could have been better if they were balcony. We were happy."
Great
40 reviews
9.2/10
1 night
From US$99
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Lesvion Hotel Hotels in Mytilene
Lesvion Hotel Hotels in MytileneLesvion Hotel Hotels in MytileneLesvion Hotel Hotels in MytileneLesvion Hotel Hotels in MytileneLesvion Hotel Hotels in MytileneLesvion Hotel Hotels in Mytilene
74
Hotels in Mytilene
A stay at Hotel Lesvion places you in the heart of Lesvos, steps from Theriade Library and Museum of Modern Art and Ecclesiastical Byzantine Museum. This hotel is 28.8 mi (46.4 km) from Sarimsakli Beach and 0.3 mi (0.4 km) from Church of Agios Therapon. Make use of convenient amenities such as complimentary wireless internet access, concierge services, and a television in a common area. Enjoy a meal at the restaurant, or stay in and take advantage of the hotel's room service (during limited hours). Quench your thirst with your favorite drink at the bar/lounge. A complimentary buffet breakfast is served daily from 7:00 AM to 10:30 AM. Featured amenities include complimentary wired internet access, dry cleaning/laundry services, and a 24-hour front desk. Make yourself at home in one of the 34 air-conditioned rooms featuring minibars and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with showers feature hair dryers and slippers. Conveniences include phones, as well as safes and desks.
Great
63 reviews
9.2/10
1 night
From US$106
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Trip.com Hotel Insights for Mytilene: Pricing, Trends & Booking Tips

Use Trip.com data-based seasonal trends and best booking times to plan and book your next hotel in Mytilene.

What is the cheapest day of the week for hotels in Mytilene?

Hotel rates in Mytilene are typically lowest on Tuesday, with average nightly rates around US$112. Monday tends to be the most expensive, averaging US$228 per night.
(Based on Trip.com data from May 18, 2025 to May 18, 2026.)
Mon
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Sun

Find unique stays in Mytilene

Immerse yourself in the vibrant atmosphere of Mytilene with our handpicked accommodation options

Best budget hotels in Mytilene

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Find Mytilene budget stays chosen for good value, comfort and location.
Ampoulos Rooms & Apartments Hotels in Mytilene
8.3/10
1 Reviews

Ampoulos Rooms & Apartments

Hotel near Mytilene
Ampoulos Rooms & Apartments offers top-notch services and amenities, ensuring guests experience utmost comfort.Complimentary internet access is available in the inn to ensure you stay connected during your visit. For guests with their own vehicle, parking facilities are provided.At the inn, utilize the convenient laundry service to maintain your preferred travel attire fresh, allowing you to pack lighter. Desire to unwind? Make the most of your visit at Ampoulos Rooms & Apartments with accessible amenities such as daily housekeeping.
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Alley Rooms Hotels in Mytilene
8.9/10
1 Reviews

Alley Rooms

Hotel near Mytilene
A stay at ALLEY ROOMS places you in the heart of Lesvos, steps from Theriade Library and Museum of Modern Art and 4 minutes by foot from Theophilos Museum. This bed & breakfast is 28 mi (45 km) from Badavut Beach and 29 mi (46.6 km) from Sarimsakli Beach. This smoke-free bed & breakfast features hiking/biking trails nearby. Enjoy a meal at the restaurant or snacks in the bed & breakfast's coffee shop/cafe. Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 9:00 AM to 11:00 AM for a fee. Featured amenities include express check-in, express check-out, and dry cleaning/laundry services. Make yourself at home in one of the 4 guestrooms. Complimentary wireless internet access is available to keep you connected. Private bathrooms with showers feature hair dryers and slippers. Conveniences include safes and irons/ironing boards, and housekeeping is provided once per stay.
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Aella Studios Hotels in Mytilene
8.9/10
0 Reviews

Aella Studios

Hotel near Mytilene
Located in Lesvos, this guesthouse is a 5-minute drive from Roman Aqueduct at Moria and 5 minutes from Archaeological Site of Thermi. This guesthouse is 32.2 mi (51.9 km) from Sarimsakli Beach and 2.5 mi (4 km) from Nisélia. Take in the views from a terrace and a garden and make use of amenities such as complimentary wireless internet access. Free self parking is available onsite. A kitchenette is outfitted with a refrigerator, an oven, and a stovetop. Complimentary wireless internet access keeps you connected, and a flat-screen television is provided for your entertainment. A private bathroom with a bathtub or shower features a rainfall showerhead and a hair dryer. Conveniences include a separate sitting area and a coffee/tea maker.
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FAQs about Mytilene hotels

What are the best places to stay in Mytilene?

Some top places to stay in Mytilene are near popular attractions like Mytilini Port and University of the Aegean—so you can quickly get to top landmarks and amenities you need.

What is the average price of a hotel in Mytilene for this weekend?

According to Trip.com’s latest 12-month data, 3-star hotels in Mytilene have an average price of US$181 per night this weekend. For 4-star hotels, the average rate is US$371 per night. If you’re seeking luxury, 5-star hotels in Mytilene typically cost US$432 per night this weekend.

What is the average nightly price of hotels in Mytilene on weekdays?

Based on Trip.com’s latest 12-month data, the average nightly rate for 3-star hotels in Mytilene on weekdays is US$168. For 4-star hotels, the average cost is around US$363 per night. For a luxury stay, 5-star hotels in Mytilene generally have an average price of US$425 per night on weekdays.

What are the best pet-friendly hotels in Mytilene?

What hotels in Mytilene offer an especially good breakfast?

Begin your day with a tasty and satisfying breakfast! Mythical Coast Wellness Retreat (price from US$111), The Loriet (price from US$89) and Theofilos Paradise Boutique Hotel (price from US$110) provide the best breakfast to start your day.

Which hotels in Mytilene provide fitness facilities?

Mythical Coast Wellness Retreat (price from US$111) offers fitness facilities to keep you active during your stay. Stay on track with your fitness goals while on the go!

What are the best hotels with a spa in Mytilene?

A spa hotel can make your trip more enjoyable with relaxing amenities. Mythical Coast Wellness Retreat (price from US$111) and Theofilos Paradise Boutique Hotel (price from US$110) are great choices for spa hotels offering quality services.

What are the best hot spring hotels in Mytilene?

Hotels with hot springs provide a perfect way to relax and recharge during your stay. Mythical Coast Wellness Retreat (price from US$111) and Theofilos Paradise Boutique Hotel (price from US$110) include hot springs for a truly relaxing experience.

Which hotels in Mytilene have pools?

The Loriet (price from US$89), Oikies Small Elegant Houses (price from US$112) and Mythical Coast Wellness Retreat (price from US$111) are excellent options for hotels with swimming pools. Book your stay to enjoy the pool and make your trip more enjoyable.

What are the best hotels in Mytilene near Mytilini Port?

Some standout hotels in Mytilene close to Mytilini Port include Theofilos Paradise Boutique Hotel (price from US$110), Blue Sea Hotel (price from US$68) and Lesvion Hotel (price from US$74), all within easy walking or transit distance of Mytilini Port, perfect for travelers wanting to explore the landmark and its surroundings.

How to get good deals on hotels in Mytilene?

Find the best hotel deals and promotions on Trip.com, available year-round for both first-time and loyal users. Please check the promotions page to see what promotions are available now on Trip.com.

More Info about Hotels in Mytilene

Number of Reviews
307
Total Properties
19
Weekday Avg. Price
US$210
Weekend Avg. Price
US$224
Trending hotel
Lesvion Hotel